Bulk MSM Powder Manufacturer in China

Wholesale Methylsulfonylmethane powder 99% pure for joint health, mobility, and anti-inflammatory support in dogs and cats. Jayoo Biotech offers factory-direct bulk supply with free samples, 1000+ tons annual export, Kosher, Halal certified quality.

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Bulk MSM Powder (Methylsulfonylmethane)

Product NameMSM powder
Other namesMethylsulfonylmethane, Dimethyl sulfone, Methyl sulfone, Sulfonylbismethane,  organic sulfur, crystalline dimethyl sulfoxide, DMSO2, (Methanesulfonyl)methane , Methane, 1,1′-sulfonylbis-dimethyl sulfone
Molecular formula(CH3)2SO2
Molecular weight94.13
Specifications99% Assay
AppearanceWhite Crystalline power
OEM ServicesCustom formulation,Pet functional feed,Pet supplement,  capsules, tablets, softgels,powder,contract manufacturing, custom logo
Bulk Packaging25kg/drum, 1kg -25kg per bag
Annual supply capacity1000 tons/year 
Benefitsreduce joint pain, ease arthritis symptoms, and lower inflammation

Jayoo Biotech is a leading MSM (Methylsulfonylmethane) powder manufacturer in China, specializing in high-purity sulfur compounds for pet joint health and nutritional supplements. Our MSM powder is widely used in pet supplements, veterinary formulations, glucosamine chondroitin MSM blends, and hyaluronic acid with MSM capsules, delivering benefits such as improved joint mobility, anti-inflammatory support, and cartilage protection; with over 1000 tons exported annually, we ensure stable supply, consistent quality, and global compliance.

What is MSM supplement?

MSM (Methylsulfonylmethane) is a naturally occurring organosulfur compound found in plants, animals, and small amounts in foods such as fruits, vegetables, and grains; it is widely used as a dietary supplement for joint and connective tissue health. With CAS No. 67-71-0, molecular formula C₂H₆O₂S, and molecular weight 94.13 g/mol, MSM appears as a white crystalline powder with excellent water solubility and high bioavailability. Available in 99% purity, it is commonly packed in 25kg/drum for bulk supply. As a leading bulk MSM supplier, Jayoo Biotech also provides OEM capsules, tablets, soft chews, and customized pet supplement formulations.

MSM Specifications

Jayoo Biotech’s MSM powder is manufactured under strict quality control, featuring ≥99.9% assay (GC method), heavy metals ≤10 ppm, lead ≤3 ppm, arsenic ≤1 ppm, cadmium ≤1 ppm, and mercury ≤0.1 ppm, ensuring maximum safety for pet applications. Residual solvents comply with USP standards, with loss on drying ≤0.5% and sulfate ash ≤0.1%, tested using internationally recognized methods such as GC, ICP-MS, and HPLC. Each batch is packaged in 25kg fiber drums with double PE lining, meeting GMP, Kosher, Halal standards, and supported by third-party testing reports, ensuring reliable quality for supplement manufacturers and global distributors.

Test ItemsSpecification
AppearanceWhite crystalline powder
Assay (GC)≥ 99.9%
Loss on Drying≤ 0.5%
Sulfate Ash≤ 0.1%
Heavy Metals≤ 10 ppm
Lead (Pb)≤ 3 ppm
Arsenic (As)≤ 1 ppm
Cadmium (Cd)≤ 1 ppm
Mercury (Hg)≤ 0.1 ppm
Residual SolventsComplies with USP standards
Packaging25kg/drum, double PE lining

MSM Manufacturing Process

Jayoo Biotech produces MSM powder through a high-purity synthesis and crystallization process, ensuring consistent quality and safety:

  • Raw material purification (DMSO base)
  • Controlled oxidation to MSM
  • Multi-stage filtration and decolorization
  • Crystallization under controlled temperature
  • Centrifugal separation and washing
  • Drying and moisture control
  • Milling and particle size standardization
  • Quality inspection (GC, ICP-MS testing)
  • Packaging in 25kg fiber drums

The final MSM powder reaches ≥99.9% purity, complies with international standards, and passes third-party testing. Custom formulations for pet supplements and MSM soft chews can be tailored to meet specific requirements.

flow chart of MSM powder manufacturing process

MSM Applications

MSM (methylsulfonylmethane) powder is a key functional ingredient widely used in pet supplement formulations, valued for its powerful joint support, anti-inflammatory, and skin health properties. As a bioavailable source of organic sulfur, MSM plays a critical role in maintaining healthy connective tissue, cartilage, and collagen synthesis, making it an essential component in supplements designed for aging or active dogs and cats. Its natural anti-inflammatory effects help reduce joint pain, stiffness, and swelling, significantly improving mobility and daily comfort in pets suffering from arthritis or joint-related conditions. Beyond joint health, MSM supports skin integrity, coat quality, and coat shine by promoting keratin production and reducing oxidative stress. It is also recognized for its ability to enhance immune function and support faster post-exercise recovery in active pets. Commonly blended with complementary ingredients such as glucosamine, chondroitin, and omega fatty acids, MSM powder integrates seamlessly into a wide range of product formats including chewable tablets, soft chews, and powdered supplements. Its proven efficacy, excellent safety profile, and high consumer demand make MSM a go-to ingredient for pet supplement manufacturers looking to develop premium, science-backed wellness products for dogs and cats.

Joint Health Supplements for Dogs & Cats

MSM is most commonly used in glucosamine chondroitin MSM formulas, where it helps support cartilage structure, reduce joint discomfort, and improve flexibility. It is ideal for aging pets or breeds prone to joint issues, making it a core ingredient in daily mobility supplements.

Anti-Inflammatory & Pain Relief Formulas

Thanks to its natural sulfur content, MSM helps reduce inflammation and oxidative stress in pets. It is widely included in supplements targeting arthritis, stiffness, and post-exercise recovery, helping pets stay active and comfortable.

Skin & Coat Health Products

MSM supports collagen production and skin repair, contributing to healthier skin and a shinier coat. It is often combined with ingredients like hyaluronic acid with MSM capsules to enhance hydration and skin elasticity in pets.

Pet Treats, Soft Chews & Functional Snacks

MSM is easy to incorporate into MSM soft chews and pet treats, offering a convenient and palatable way for daily supplementation. These formats are especially popular among pet owners looking for stress-free ways to support joint and overall health.

Where to buy bulk MSM Powder?

Looking for a reliable MSM (Methylsulfonylmethane) powder supplier in China? Jayoo Biotech is a trusted factory manufacturer and wholesale supplier of high-purity MSM powder for pet supplements and veterinary use. We offer bulk and wholesale supply, OEM capsules, tablets, MSM soft chews, and customized formulations including glucosamine chondroitin MSM and hyaluronic acid with MSM capsules.

Backed by GMP, Kosher, and Halal certifications, third-party testing reports, and strong global export experience, Jayoo Biotech ensures consistent quality and international compliance for supplement brands, distributors, and importers worldwide. Free samples are available upon request. Contact us today for competitive pricing and dependable supply from a professional MSM manufacturer in China.

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