Bulk Sodium Hyaluronate Powder Manufacturer in China

High-purity grades 99% with customizable molecular weights, ensuring optimal performance for different formulations. Factory-direct pricing, stable bulk supply, OEM capsules & tablets, and fast global export service, all backed by GMP production, third-party testing, and international certifications.

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Bulk Sodium Hyaluronate Powder

Product NameSodium hyaluronate
Other names Sodium Hyaluronan,Sodium (1→4)-O-β-D-glucopyranosyl-(1→3)-2-acetamido-2-deoxy-β-D-glucopyranoside,SH,Hyaluronic Acid
CAS Number9067-32-7
Molecular FormulaC14H22NNaO11
Molecular Weight403.31
Specifications 100,000-2,000,000Da
Appearance White to off-white powder
BenefitsJoint health,  Hydration, immune regulation and anti-inflammatory 
OEM ServicesCustom formulation,Pet functional feed,Pet supplement,  capsules, tablets, softgels,powder,contract manufacturing, custom logo
Bulk Packaging25kg/drum, 1kg -25kg per bag
Annual supply capacity1000 tons/year 

Jayoo Biotech is a leading bulk Sodium Hyaluronate powder manufacturer in China, specializing in high-purity hyaluronic acid ingredients for global B2B markets. With annual exports exceeding 1,000 tons, we supply premium-grade sodium hyaluronate to supplement brands, cosmetic manufacturers, and pharmaceutical companies worldwide. Known for its excellent moisturizing, joint lubrication, and skin-repair properties, sodium hyaluronate is widely used in nutraceuticals, skincare, medical devices, and eye care applications. Backed by advanced production technology and strict quality control, Jayoo Biotech ensures consistent supply, competitive pricing, and OEM solutions for global distributors.

What is Sodium Hyaluronate?

Sodium Hyaluronate is the sodium salt form of hyaluronic acid, a naturally occurring polysaccharide found in human connective tissues, skin, and synovial fluid, as well as produced via microbial fermentation (Streptococcus or Bacillus strains). It has a CAS number of 9067-32-7, molecular formula (C14H20NO11Na)n, and variable molecular weight ranging from 10,000 to 2,000,000 Da depending on application. This ingredient appears as a white crystalline or amorphous powder, highly soluble in water, forming a clear, viscous solution with excellent bioavailability and skin penetration. Common specifications include 99% purity with different molecular weights (low, medium, high). It is typically packaged in 25kg drums for bulk supply. Jayoo Biotech is a leading bulk sodium hyaluronate supplier in China, also offering OEM capsules, tablets, and customized formulations for dietary supplements and cosmetic brands.

Sodium Hyaluronate Specifications

Jayoo Biotech’s Sodium Hyaluronate powder is produced under strict quality control standards to ensure stable purity, safety, and performance for nutraceutical, cosmetic, and pharmaceutical applications. According to the specification sheet, the product appears as a white to off-white powder, with Glucuronic Acid ≥44.5% and Sodium Hyaluronate content ≥87.0 g/100g. The average relative molecular weight ranges from 100,000 to 2,000,000 Da, while pH (1 mg/ml, 25°C) is controlled at 6.0–8.0 and transmittance (1 mg/ml) reaches T600nm ≥99.0%, indicating excellent purity and solution clarity. Moisture is controlled at <10%, ash content at <13 g/100g, lead <2 mg/kg, arsenic <1 mg/kg, bacteria counts <100 CFU/g, and yeasts & molds ≤50 CFU/g, with coliform bacteria and Staphylococcus aureus both testing negative. Packed in 25kg/drum with a shelf life of 3 years, this product is suitable for global bulk buyers seeking reliable quality. At Jayoo Biotech, every batch is manufactured with a strong focus on product consistency, safety, and compliance to support supplement manufacturers, cosmetic brands, and distributors worldwide.

Test ItemSpecification
Product NameSodium Hyaluronate
CAS No.9067-32-7
Molecular FormulaC14H22NNaO11
Molecular Weight403.31
Shelf Life3 Years
Pack Size25Kg/Drum
AppearanceWhite to off-white powder
Glucuronic Acid (%)≥44.5
Sodium Hyaluronate Content (g/100g)≥87.0
Intrinsic Viscosity (dL/g)Measured value
Average Relative MW (Da)100,000-2,000,000 Da
pH (1mg/ml, 25°C)6.0-8.0
Transmittance (1mg/ml)T600nm ≥99.0%
Moisture<10
Ash Content (g/100g)<13
Lead (mg/kg)<2
Arsenic (mg/kg)<1
Bacteria Counts (CFU/g)<100
Yeasts & Molds (CFU/g)≤50
Coliform BacteriaNegative
Staphylococcus AureusNegative
StorageSealed package, store in a dry and cool place

Sodium Hyaluronate Manufacturing Process

Jayoo Biotech produces Sodium Hyaluronate powder using a controlled fermentation and purification process to ensure high purity and consistent quality. The process begins with strain activation in shake flasks, followed by scale-up in a seeding tank and industrial fermentation, where hyaluronic acid is biosynthesized. The resulting crude product is then dissolved and purified through alcohol precipitation, effectively removing impurities and proteins.

Next, the material undergoes dehydration and secondary alcohol precipitation, followed by filtration and centrifugation to further refine purity. The intermediate product is subjected to strict quality testing, ensuring it meets required specifications. After that, it is dried into fine powder form, resulting in high-purity sodium hyaluronate. Finally, the product is packed in 25kg drums under controlled conditions to maintain stability and shelf life.

This standardized process ensures that Jayoo Biotech’s Sodium Hyaluronate achieves stable molecular weight (100,000–2,000,000 Da), high purity, and compliance with international quality standards, making it ideal for bulk supply to supplement, cosmetic, and pharmaceutical manufacturers.

flow chart of Sodium Hyaluronate Manufacturing Process

Sodium Hyaluronate Applications

Thanks to its excellent water-binding capacity, biocompatibility, and high bioavailability, Sodium Hyaluronate has become a versatile ingredient across multiple industries. Its ability to retain moisture, improve joint lubrication, and support tissue repair makes it highly valuable in both health and beauty formulations. From dietary supplements and advanced skincare products to pharmaceutical preparations and eye care solutions, sodium hyaluronate is widely used by global manufacturers seeking effective, science-backed functional ingredients.

Dietary Supplements

Sodium hyaluronate is widely used in capsules and tablets for joint health, skin hydration, and anti-aging support, improving elasticity and lubrication.

Cosmetics & Skincare

A key ingredient in creams and serums for deep hydration, wrinkle reduction, and skin repair, especially in premium cosmetic formulations.

Pharmaceutical & Medical

Used in injections, eye drops, and osteoarthritis treatments, providing lubrication and tissue protection.

Eye Care Products

Essential for sodium hyaluronate eye drops, helping relieve dry eye symptoms and improving ocular moisture retention.

Where to buy bulk Sodium Hyaluronate Powder?

Looking for a reliable bulk Sodium Hyaluronate supplier in China? Jayoo Biotech is your trusted factory-direct manufacturer, offering wholesale sodium hyaluronate powder with consistent quality and competitive pricing. We support global buyers including bulk sodium hyaluronate distributors, resellers, and OEM brands with flexible solutions such as capsules, tablets, and custom formulations.

Our products include standard sodium hyaluronate, sodium acetylated hyaluronate, hydrolyzed sodium hyaluronate, and pharmaceutical-grade materials for eye drops applications. All products are manufactured under GMP conditions and certified with Kosher, Halal, and international quality certificates, supported by third-party testing reports.

Whether you are a bulk sodium hyaluronate reseller or wholesale distributor, we provide:

  • Factory-direct pricing
  • Stable bulk supply
  • OEM/ODM services
  • Free samples
  • Full documentation & COA

Contact Jayoo Biotech today to partner with a leading sodium hyaluronate manufacturer in China and grow your global business.

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